Ozempic, Wegovy, Mounjaro for PCOS
1. What Are Mounjaro for pcos, Wegovy, and Olympic?
One of the many medications categorized as GLP-1 receptor agonists is ozempic. Semaglutide is the chemical name. You should take Ozempic, a self-injectable diabetes medicine, once each week. The year 2017 saw its initial approval for use.
Ozempic’s equivalent, Wegovy, was authorized as a weight-loss medication in 2021. Wegovy contains a higher concentration of semaglutide, which is the only distinction.
Out of these three treatments that are identical, Mounjaro for pcos is the most recent. The active molecule’s generic name is tirzepatide. Mounjaro, which will be approved in 2022 for type 2 diabetes, is in the same category as Ozempic. However, it also affects the GIP hormone receptor. This is meant to increase its potency.
2. Why Use Ozempic (or Its Alternatives) for PCOS Symptoms?
For the majority of PCOS sufferers, insulin resistance is a major issue.
Success Story of Leeanne’s Weight Loss and PCOS
Transporting glucose from the blood into cells is just one of insulin’s many functions. Your body responds to insulin less effectively if you have insulin resistance. Your body responds to this issue by maintaining constant high insulin levels. not only when it is required. The majority of PCOS-afflicted overweight women are affected by this unhealthy situation. Many PCOS women with normal weights are also insulin resistant.
One of the underlying causes of all PCOS symptoms is insulin resistance. Insulin resistance leads to weight gain and higher risks of heart disease when combined with a “poor diet”. In addition to bringing on irregular menstrual periods, it aggravates hirsutism and acne.
The main influence on insulin resistance comes from diet. Because of this, people who take part in my free 30-Day PCOS Diet Challenge start to experience incredible results after just a few weeks of using my PCOS meal plans. Their weight isn’t the only thing that gets better. Their cycle changes, and they experience less acne and unsightly hair.
Another method to reverse insulin resistance is to take Ozempic, Wegovy, or Mounjaro. For women with PCOS, this may aid in reestablishing a healthier hormone balance.
The management of blood glucose levels is improved by both Ozempic and Wegovy. By assisting with weight loss, this indirectly reduces insulin resistance.
Mounjaro also benefits from this. But in addition to promoting weight reduction, it may also directly enhance insulin sensitivity via a different method.
3. How Do They Aid Insulin Resistance and Insulin Sensitivity?
Insulin-resistant PCOS is combated by Ozempic and Mounjaro in various methods. All of these outcomes result in weight loss.
Only after eating do they promote insulin production. This lessens blood sugar peaks. Insulin levels that are persistently elevated due to insulin resistance are less healthy than the post-meal rises in insulin production from Ozempic or Mounjaro.
In general, Mounjaro and Olympic can reduce blood sugar levels. They accomplish this by stopping the liver from releasing glucose.
These procedures prolong your feeling of fullness. As a result, you eat less, which lowers your need for insulin.
Additionally, these medications might help control fat metabolism and reduce inflammation.
4. Which Is Better, Mounjaro for pcos vs. Olympic for pcos?
Results from a trial comparing Mounjaro for pcos and Ozempic for pcos were published in 2021. Mounjaro’s producer, Eli Lilly, provided funding for this study.
They discovered that in terms of weight loss and insulin sensitivity, Mounjaro outperformed Ozempic. This implies that Mounjaro might be better than Olympic. More tests, however, are required to validate these results. Higher doses of Ozempic/Wegovy have not yet been compared to Mounjaro as of the time of writing.
5. Are These Medicines Effective for PCOS Fertility?
PCOS-afflicted obese women experience a number of reproductive difficulties. This includes lowered egg quality, messed up embryo development, and decreased uterine receptivity.
Insulin resistance and obesity are the key contributors to this decreased fertility.
Reducing body weight is the greatest strategy for obese women with PCOS to boost fertility and pregnancy outcomes. A 5–10% weight decrease can have a significant impact.
For those who are overweight, Ozempic, Wegovy, and Mounjaro result in weight loss. They can therefore indirectly increase fertility in a portion of the PCOS population.
6. Is Ozempic More Effective Than Metformin?
One of the most well-known drugs for insulin sensitization is metformin. Patients with PCOS are frequently prescribed it to encourage weight loss and/or treat infertility.
However, metformin has recognized negative effects. Metformin is frequently intolerable by patients because of this. Long-term use is also known to cause nutritional depletion. Alternatives like inositol and berberine are gaining popularity because of the limited net benefits of metformin for PCOS.
Another viable choice for PCOS sufferers would be ozempic. Ozempic and metformin are contrasted side by side here. For PCOS patients, research is being done to compare Ozempic’s advantages in terms of weight loss to those of metformin.
It’s vital to keep in mind that Ozempic only functions while you take it, just like with all insulin-sensitizing drugs. Anyone who wishes to control PCOS over the long run should continue to place a high premium on eating well.
7. How Dangerous Are the Ozempic, Wegovy, and Mounjaro Routes?
New medications include Mounjaro, Wegovy, and Olympic. Although they have passed regulatory safety evaluations, there is little information on their long-term safety.
Warnings
The prescribing material for these medications lists a few recognized dangers. For instance, it’s unknown if taking Ozempic while pregnant is safe or if it enters breast milk. Two months before you intend to become pregnant, the manufacturer advises against taking it. Mounjaro may harm fetuses, according to Eli Lilly’s warning based on animal studies.
Clinical trials of Ozempic have revealed pancreatic inflammation. For this reason, Mounjaro has not been investigated in patients with a history of pancreatitis.
Ozempic and Mounjaro may raise the risk of diabetic retinopathy for those with type 2 diabetes. Additionally, these medications should not be used if you have severe kidney injury or gallbladder disease. Studies on animals have sparked worries that drugs like Mounjaro and Ozempic may lead to thyroid malignancies, including cancer.
Negative effects
One of the most intriguing side effects of Ozempic (and Mounjaro) is “Ozempic Face”. This is where, as a result of rapid weight reduction, your face sags and your skin aged. This might be inevitable. In order to treat this negative effect, some doctors could advise face fillers.
More than 5% of Ozempic patients experience negative side effects. The most frequent of them are stomach pain, diarrhea, vomiting, nausea, and constipation. At the injection site, some people may feel redness, swelling, or itching. The side effects of Mounjaro are comparable and dose-dependent.
You should be cautious of hypoglycemia since Ozempic reduces blood glucose levels. This is particularly crucial if you already take other blood sugar-lowering drugs.
Drug Interactions
Most importantly for PCOS, this list also contains:
both oral hypoglycemics and insulin.
Diuretics are medications that lower blood pressure.
such as ethinyl estradiol, levonorgestrel, and norethindrone (progesterone), are hormone-related drugs. These are employed in contraception.
Levothyroxine and other thyroid medicines are used to treat hypothyroidism.
Numerous antibiotics, antipsychotics, and corticosteroids may all interact negatively with ozempic.
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FAQS
Which medicine is best for polycystic ovaries?
For PCOS patients who are trying to get pregnant, clomifene may be the first medication suggested. Ovulation, or the monthly release of an egg from the ovaries, is promoted by clomifene.If clomifene is not successful in promoting ovulation, metformin may be recommended as a fallback treatment.
What is the best weight loss medication for PCOS?
Metformin, acarbose, sibutramine, and orlistat (Xenical) are effective weight-loss medications that have been specifically examined in women with PCOS (together with lifestyle changes). The drug of choice for treating obesity or weight loss in PCOS individuals is likely to be metformin.
Can Mounjaro cause irregular periods?
Yes, Mounajaro might have an impact on your period.
Is Mounjaro approved for weight loss?
At this time, Mounjaro is not authorized for weight loss. But in late 2023, the FDA is anticipated to examine it and perhaps approve it for this usage. Wegovy is licensed for chronic weight management in adults and adolescents ages 12 and older.
How I finally lost weight with PCOS?
12 Tips for Losing Weight While Having PCOS
Eat fewer carbohydrates.
Consume a lot of fiber.
Consume adequate protein.
Consume good fats.
Consume fermented food.
Become mindful when you eat.
Eat less processed meals and sugar-added products.
cut the inflammation.
What is the latest treatment for PCOS?
Although metformin and other insulin sensitizers have been used for many years to treat PCOS metabolic dysfunction, more recent medications such incretin mimics and SGLT2 inhibitors have been found to be more successful at lowering weight and cardiovascular risk.
How to take mounjaro for weight loss?
Usually, Mounjaro is prescribed at a low dosage by your doctor, who will gradually increase it to the ideal level for you. Depending on how well Mounjaro is helping you lose weight, your doctor will prescribe a certain dosage. 2.5 milligrams (mg) used once a week for four weeks is the typical starting dose of Mounjaro for weight loss.
What is the injection for PCOS weight loss?
There is evidence that medical treatment utilizing weight-management medicines may alter the physiological and behavioral factors that cause weight gain in PCOS-affected women. Saxenda is an FDA-approved injectable medication available only by prescription.
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